A New York Times interview with Nancy Andreasen, author of books, such as The broken brain. She reports what she calls the "big finding" that people with schizophrenia are losing brain tissue at a more rapid rate than healthy people of comparable age. Some are said to be losing as much as 1% per year. This data comes from an unpublished study following up schizophrenics. Andreasen seems to suggest the finding may be due to prefrontal cortical atrophy caused by antipsychotic drugs.
Andreasen says she "sat on" the findings because she didn't want people who need the drugs to stop taking them. Actually, there may be other non-specific reasons why people given antipsychotics have less brain tissue. Any drug effect on brain tissue also may not be of much consequence. But, the problem is the lack of debate. Andreasen is so wedded to the biomedical hypothesis that any potential negative repercussions of her views are suppressed.