rapid response to the debate about whether antidepressants are over-prescribed, which I have mentioned previously (eg. see post), makes reference to his blog entry that blames the media for distorting findings and misleading patients. He makes clear that he is worried that depressed patients may not take antidepressant medication.
I think it is clear that Irving Kirsch is making the case that antidepressants are amplified placebos (see previous post). Preda doesn't really deal with this issue. As I keep saying, there doesn't seem to be any argument that the drug placebo difference in clinical trials is small. The question is whether it can be explained by expectancy effects through unblinding in clinical trials.