Saturday, June 21, 2014

The sense in saying antidepressants don't work

According to a Times article, Sir Simon Wessely, President-elect of the Royal College of Psychiatrists, thinks it is "nonsense to say that antidepressants do not work". I presume he's saying that antidepressants are more than placebos. He may know more than I do, but he doesn't seem to think that the small effect size in clinical trials could be due to placebo amplification due to unblinding (eg. see previous post).

I guess he has to believe this as head of the Royal College of Psychiatrists. My scepticism means I'm never going to fulfill this role! It's alright for Simon to say that he doesn't really buy parents promoting the idea that their children who get into Oxford are mildly autistic. And, that modern services couldn't be less well designed to join up physical and mental health care. But it's beyond the pale to suggest that psychotropic medication is not effective.

1 comment:

Unknown said...

Thanks for the post. I really like reading about studies and experiments, and I agree with you. They can't really conclude anything, because they didn't make it a blind study. I think they should do it again, but have it be double blind with groups with treatment and with the placebo.